Along with the increasing demand for oil and natural gas by various world economies, the operating pressure of the pipelines is also increasing which results in increasingly severe consequences of any failures for both society and industry. In the last decade, large diameter heavy wall high strength low alloy (HSLA) steel pipelines have attracted attention for long distance high pressure oil and gas transportation in the North America. From a pipe production perspective, the welding technology of these heavy gauge pipes with the thickness as high as 19 mm to 25.4 mm has been remained challenging and under development. Multi-wire tandem submerged arc welding (MW-TSAW) process has been extensively used for the fabrication of heavy gauge pipes with the aim of a higher productivity; however, increasing the number of electrodes results in a relatively higher welding heat input and technical issues with consequent adverse effects on the properties of the ﬁnal product. Accordingly, this paper elucidates the challenges and potential solutions to welding heavy gauge HSLA steel pipes from both technical and metallurgical perspectives.